Started by Goldenwolf, here's my contribution.
...Its a meme about your own version of werewolves. Because they're mythological, and can pretty much be any version of a human turning into a wolf.
Original cause of "werewolfism":
An alien intelligence that refers to itself as "Four One" created numerous mythical creatures, including werewolves, while attempting to understand something it knew it lost during its own evolution many millennia ago. The lycanthrope "virus" is not technically a virus, as it is a too complex structure that hybridizes earth-based and Four One cellular make-up.
How can one become a werewolf?:
The bite of an infected individual, or any other contact with body fluid--the same ways that one can get hepatitis or HIV. Maternal-fetal transmission is 100%; children of lycanthropic mothers are born with it.
Somewhat extended, with an approximate doubling from human life expectancy because of enhanced regenerative capabilities, assuming one is inf